ABPS

Aim To study the physicochemical properties and the structure of Achyranthes bidentata polysaccharide ( AbPS ) .

目的研究牛膝 多糖 的理化性质与结构.

Results: Hela cell adherence assay data showed that the ABPS can obviously inhibit the adherence at the concentration of 0 8mg/ ml, the adherence rate was reduced from 257 0 ± 5 2 organisms/ cell to 63 6 ± 3 6 organisms/ cell.

结果：发现牛膝多糖浓度为0.8mg/ml时，对细菌的细胞粘附抑制最为明显，粘附率由（257.0±5.2）个细菌/细胞降低到（63.6±3.6）个细菌/细胞。

A Study of Synthesis of Atactic branched Polystyrene ( ABPS) in One Step

一步法合成无规支化聚苯乙烯（ABPS）的研究

Conclusion: ABPS can induce the expression of cytokines in the macrophages, and activate the macrophages.

结论: 牛膝多糖可诱导巨噬细胞表达细胞因子, 并对巨噬细胞具有激活作用.

By the methylation method and GC MS analysis, we studied the distribution of carboxymethyl groups in the sugar backbone of CM AbPS and conclude that the carboxymethyl groups mainly substitute on 4 position of the fructofuranose of the sugar backbone.

并通过样品甲基化和GC MS分析，对羧甲基牛膝多糖糖链中羧甲基的分布进行了研究，结果表明羧甲基牛膝多糖中羧甲基主要取代在糖链中呋喃果糖的4位上。

In response, the ABPS has established a new board of certification in disaster medicine.

相应，ABPS新建立了灾难医生认证委员会。

ABPS can induce the expression of cytokines in the macrophages, and activate the macrophages.

牛膝多糖可诱导巨噬细胞表达细胞因子，并对巨噬细胞具有激活作用。

CONCLUSIONS: ( 1) ABPS can rectify the unequilibrium of Th1/ Th2 cytokines in PBMC from patient with asthma or lung cancer.

结论：（1）应用牛膝多糖能初步纠正肺癌和哮喘患者Th1和Th2细胞因子的失平衡。

RESULTS: GM-CSF expression induced by ABPS obviously increased in mouse brain tissue.

结果：不同浓度的ABPS对小鼠脑组织表达GM CSF有明显的促进作用，浓度范围为2～6mg·ml-1之间，最佳浓度为4mg·ml-1。

The bioactive results suggest that hydroxyalkylated AbPS were able to inhibit the growth of these two kind of tumors, and improve the activity of NK cell of mice bearing Lewis lung cancer.

结果表明，不同取代度的羟烷基化牛膝多糖对Lewis肺癌和B16黑色素瘤均有明显的抑制作用，同时能明显促进Lewis肺癌小鼠的NK细胞活性。

OBJECTIVE To study the activated effects of Achyranthes bidentata polysaccharides ( ABPS) on human monocytes in vitro, inducing HLA-DR_(α) surface molecules expression of monocytes.

目的：研究牛膝根多糖（ABPS）在体外对单核细胞活性的调节及诱导单核细胞HLA-DRα表面分子的表达。