amphotericin

Objective : To prepare amphotericin B-polybutylcyanoacrylate-loaded nanoparticle ( AmB-PBCA-NP ) and to assess their ability to pass the blood-brain barrier.

目的: 制备携载两性霉素的聚氰基丙烯酸正丁酯纳米粒 ( AmB -PBCA-NP ),研究其对血脑屏障的透过能力.

Amphotericin B in liposome revealed fine stability.

两性霉素B在脂质体中具有优良的稳定性.

Sensitivity results to nine antifungals showed that 5-flucytosine, fluconazole, clotrimazole, amphotericin B, and nystatin had higher drug sensitivity to these fungi.

在9种抗真菌药药敏试验中，5-氟胞嘧啶、氟康唑、克霉唑、两性霉素B、制霉菌素有较高的敏感性。

The rate of C. albicans susceptibility to amphotericin B, fluconazole, flucytosine ( 5-FC) and itraconazole were 100%, 94.6%, 92.86% and 57.1%, respectively.

白色念珠菌对两性霉素B、氟康唑、氟胞嘧啶和伊曲康唑的敏感性分别为100%、94.6%、92.86%和57.1%。

Basal medium was composed of penicillinum, phytomycin, amphotericin B and DMEM/ F12 containing B27 annex solution of 0.02 volume fraction.

基础培养基组成：含青霉素、链霉素、两性霉素B及体积分数为0.02B27添加液的DMEM/F12。

Objective to study in vitro the antibiotic sensitivity of amphotericin B and fluconazole, which are commonly used to treat fungal corneal ulcers caused by fusarium, Candida and aspergillus.

目的探讨两性霉素b（amphotericinb）和氟康唑（fluconazole）这两种常见的抗真菌药物对眼科常见的致病真菌（镰刀菌属、念珠菌属、曲霉菌属）的体外抗菌活性。

Amikacin and piperacillin/ tazobactam were of high sensitivity for the most bacteria, and 5 flucytosine, amphotericin or fungicidin were found possessing the sensitivity to common fungus as high as 95 7 100%.

常见真菌对5氟胞嘧啶、两性霉素和制霉菌素的敏感率为95.7%~100%。

After 3 weeks of amphotericin B liposome treatment, swelling of the upper arm alleviated and pain disappeared.

对上肢感染组织行清创术、截肢，并予以两性霉素B脂质体治疗3周。

AIM: To observe the influence on peripheral blood figure by amphotericin B ( AMB) combined with flucytosine ( 5 FC) in the treatment of the patients with cryptococcus meningitis.

目的：探讨两性霉素B（AMB）联合5-氟胞嘧啶（5-FC）治疗新型隐球菌性脑膜炎时对患者外周血象的影响。

Effects of Aerosol Inhalation of Amphotericin B on Pulmonary Mycotic Infection

雾化吸入二性霉素B治疗肺部霉菌感染的临床观察

An Intravitreal Amphotericin B Drug Delivery System for the Treatment of Experimental Aspergillus Fumigatus Endophthalmitis

两性霉素B缓释系统治疗烟曲霉菌性眼内炎的药效学研究

Pharmacokinetics of amphotericin B liposome eye drop in aqueous humor of rabbit

两性霉素B脂质体滴眼液在兔房水中的药动学

Study on the Method for Determination of the Particle Size of Liposome Amphotericin B

两性霉素B脂质体粒度测定方法研究

Influence on heart, live and kidney from combined amphotericin B and flucytosine

两性霉素B和5-Fc联合用药对心、肝、肾功能的影响

Study on the Purification Process of Amphotericin B Using Macroporous Adsorption Resins

大孔树脂吸附法纯化两性霉素B的研究

Results: The respective 90% MICs ( MIC 90) of ketoconazole, 5 flucytosine, itraconazole, amphotericin B and fluconazole against 102 isolates of Candida albicans were 0.25, 0.5, 0.5,2 and 8 μ g/ ml.

结果：酮康唑、氟胞嘧啶和伊曲康唑对102株白色念珠菌MIC较低，其MIC90分别为0.25μg/ml、0.5μg/ml和0.5μg/ml。两性霉素B和氟康唑MIC90分别为2μg/ml和8μg/ml。

Susceptibility results show that Candida infections are highly susceptible to fluconazole, flucytosine and amphotericin B;

结论念珠菌感染中以白色念珠菌最为多见，药敏结果显示氟康唑、氟胞嘧啶、两性霉素B敏感性高；

In the past fie years, there has been an incremental reduction in the morbidity associated with empirical amphotericin therapy.

在过去的5年中，两性霉素治疗相关的并发症的发生得到了进一步的降低。

Result: Candida species are resistant to terbinafine, medium susceptible to fluconazole 、 ketoconazole 、 miconazole and clotrimazole, high susceptible to nystatin 、 itraconazole 、 amphotericin B and flucytosine.

结果：检测出的念珠菌对特比萘芬耐药，对氟康唑、酮康唑、咪康唑、克霉唑中度敏感，对制霉菌素、伊曲康唑、两性霉素B、氟胞嘧啶高度敏感。

Drug resistance rate from high to low of the frequently used antimycotic drug for Candida mycoderma bacteria are Itraconazole, fluconazol, econazole, amphotericin in turns.

常用抗真菌药物对假丝酵母菌耐药率由高到低依次是伊曲康唑、氟康唑、益康唑，最低为两性霉素。

Influence on peripheral blood figure from combined amphotericin B and flucytosine in patients with cryptococcus meningitis

两性霉素B和5-氟胞嘧啶合用对隐球菌脑膜炎患者外周血象的影响

Methods After removed the focus of the fungal corneal ulcer, the corneal was covered the soft lenses soaked with 0.2% Amphotericin B.The soft lenses were removed for cleaning and disinfecting every three days.

方法角膜病灶切除后覆盖用0.2%二性霉素B眼药水浸泡过的治疗软镜，每3天取下治疗软镜清洁消毒1次。

An experimental study of the therapeutic effect of interleukin-2 and interleukin-12 with and without amphotericin B on pulmonary fungal infection

白细胞介素2及12对小鼠肺部曲霉菌感染治疗作用的实验研究

Clinical effect of amphotericin B on patients with fungus infection of lung

两性霉素B治疗肺部真菌感染的疗效观察

Results Amphotericin B is a potent antifungal agent with a broad antifungal spectrum.

结果两性霉素B是抗菌谱广、抗菌作用强的抗真菌药物.

Preparation of Amphotericin B Microemulsion and Its Transdermal Absorption Determination of entrapment efficiency of amphotericin B liposome by mini-column centrifugation-HPLC

两性霉素B微乳的制备及体外经皮渗透研究微柱离心-HPLC法测定两性霉素B脂质体包封率

In conclusion, treatment with amphotericin B and itraconazole has negligible efficacy in CNS aspergillosis.

结论:联用两性霉素B和伊曲康唑治疗CNS曲霉病无明显疗效.

Evaluation on Overseas Application of New Dosage Forms of Amphotericin B

国外两性霉素B新剂型在临床的应用评价

Content determination of amphotericin B and its related substances by HPLC

高效液相色谱法测定两性霉素B含量和相关物质

For preparation slow release formulation, amphotericin B has been encapsulated with liposome by REV ( Reverse-phase-evaporation ) method .

提要两性霉素B脂质体缓释体系可通过逆相蒸发 法制 得.