choline acetyltransferase

Conclusion: Hydergine improved dysfunction of learning and memory in VD, suggested that hydergine restored expression of choline acetyltransferase mRNA.

结论：喜得镇改善血管性痴呆小鼠学习、记忆成绩与其恢复海马低水平的胆碱乙酰转移酶mRNA有关。

The choline acetyltransferase ( CHAT) and the molecular forms of acetyl-cholinesterase ( ACHE) activites in various brain regions of 20-day-old hypothyroid and hyper-thyroid rats were measured.

对20日龄的甲亢及甲减大鼠的海马、大脑皮层、前脑基底和小脑中乙酰胆碱转移酶（CHAT）、乙酰胆碱酯梅（ACHE）各亚类的活性进行了测定。

OBJECTIVE : To observe the changes of choline acetyltransferase activity in rat hippocampus after ischemia reperfusion.

目的: 观察大鼠脑缺血再灌注后海马组织胆碱乙酰基转移酶活力的动态变化.

the brains after the rats decapitated were harvested on the 1st, 7th and 15th day respectively for colorimetric determination of the choline acetyltransferase activity in hippocampus.

各组大鼠分别于术后第1,7,15d断头取脑，用比色法测海马组织胆碱乙酰基转移酶活力。

The learning and memory abilities were detected by step down test and step through test, the activity of brain choline acetyltransferase ( ChAT) and the muscarinic receptor ( MR) density were determined by 3H acetyl CoA binding analysis and 3H QNB binding tests respectively.

用避暗法及跳台法测定动物的学习记忆功能，用放射配基结合分析法分别测定脑胆碱乙酰转移酶（ChAT）活性和M受体密度。

MAIN OUTCOME MEASURES: Determination of the choline acetyltransferase activity in the groups.

主要观察指标: 大鼠脑海马组织胆碱乙酰基转移酶活力的测定.

Objective: To observe the effect of hydergine on choline acetyltransferase mRNA in neuron of hippocampus in mice with vascular dementia.

目的：观测喜得镇对血管性痴呆小鼠海马神经元胆碱乙酰转移酶mRNA变化的影响，以探讨胆碱乙酰转移酶mRNA变化在血管性痴呆发病中的作用及喜得镇对此变化的机制。