coagulase

Objective To investigate the contamination incidence of coagulase-negative staphylococci ( CNS) in blood culture.

目的调查血培养中凝固酶阴性的葡萄球菌（CNS）血样本的污染率。

Coagulase negative staphylococci are the commonest blood culture isolate from infants on neonatal intensive care units.

凝固酶阴性葡萄球菌是新生儿加护病房最常见血液阳性培养.

Objective To invetigate the condition of erm genes in methicillin resistant coagulase negative staphylococci ( MRCNS ).

目的　探讨耐甲氧西林凝固酶阴性葡萄球菌 ( MRCNS ) erm基因的存在状况.

clinical features and drug resistance of coagulase negative staphylococcus septicemia of newborn

新生儿凝固酶阴性葡萄球菌败血症的临床及耐药性分析

[ Objective] To study the influence of slide coagulase test on determining the staphylococcus aureus ( SA) with GPI assay.

目的了解玻片法凝固酶试验在GPI卡鉴定金黄色葡萄球菌（SA）中的影响。

Conclusion Different anticoagulants can affect the results of slide method and test tube method coagulase tests.

结论不同抗凝剂可影响玻片法、试管法血浆凝固酶试验的结果。

Gram positive bacteria mainly included Coagulase negativeStaphylococcus ( CNS), Staphylococcus aureus and Enterococcus.

革兰阳性菌中主要为凝固酶阴性葡萄球菌（CNS）、金黄色葡萄球菌、肠球菌，耐药性严重。

Results The altered DNA sequence of coagulase in 1 strain of S . aureus was found.

结果检测到1株金黄色葡萄球菌凝固酶基因序列有改变.

Coagulase-negative staphylococci ( CNS) have become the most common cause of bovine mastitis.

凝固酶阴性葡萄球菌（CNS）已经成为引起奶牛乳腺炎的常见病原菌，通常引起隐性乳腺炎或者表现温和的临床型乳腺炎。

Methods Retrospectively analyze coagulase-negative staphylococci in blood culture from 97 hospitalized patients at our Hospital from 2004 to 2006. We differentiated true bacteremia from contamination by using a criterion reviewed from published papers.

医院耐甲氧西林葡萄球菌感染的生态学特征方法回顾分析2004-2006年从本院住院患者血中分离到CNS的病例共97例，判定是菌血症还是血样本污染。

Objective To explore the risk factors of coagulase negative staphylococcus induced nosocomial infection.

目的研究凝固酶阴性葡萄球菌（CNS）院内感染的危险因素。

Methods: A retrospective analysis of coagulase negative staphylococci in blood culture from 70 hospitalized patients in Peking Union Medical College Hospital from 1995 to 1999 was done.

方法：对本院1995～1999年血中分离到CNS的70例住院患者进行回顾性分析，判定是菌血症还是血样本污染。

Results In slide method, the positive rate of coagulase test was 98.53% with sodium citrate as anticoagulant and 95.59% with EDTA-K 2 as anticoagulant, respectively, there was no significant difference between two anticoagulants;

结果玻片法试验：枸橼酸钠抗凝人血浆凝固酶阳性率为98.53%，EDTA K2抗凝人血浆凝固酶阳性率为95.59%，二者差异无显著性（P0.05）。

Coagulase negative staphylococcus became the main opportunistic pathogen of gram-positive cocci in hospital acquired infections;

凝固酶阴性葡萄球菌为医院获得性感染革兰阳性球菌主要条件致病菌；

mrsa and mrcns accounted for 63% and 77% of s aureus and coagulase negative staphylococci respectively, no vancomycin resistant strains were found.

耐甲氧西林金黄色葡萄球菌（MRSA）和耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）分别占金黄色葡萄球菌（金葡菌）和凝固酶阴性葡萄球菌的63%与77%，无万古霉素耐药株。

The most common bacteria isolated from the conjunctiva are small numbers of coagulase-negative staphylococcus and diphtheroids.

从结膜最常分离的细菌包括少量的凝固酶阴性葡萄球菌和类白喉菌属.

A systematic identification including staining, morphology, cultural characters, biochemical properties, serological reaction, pathogenicity, sensitivity to antimicrobial agents and plasma coagulase test was done for all isolates.

对全部分离菌进行了系统鉴定，包括形态、染色、培养特性、生化特性、血清学反应、致病力、对抗菌剂的敏感性和血浆凝固酶试验等。

Method: From july in 2001 to October in 2003,81 SA strains were obtained. All clinical isolates from the second affiliated hospital, Dalian medical university. All strains were identified by the Bacto coagulase plasma test and API system estimated.

方法：标本来自2001年7月~2003年10月大连医科大学附属第二医院收集的81株金黄色葡萄球菌，常规分离临床标本，经凝固酶试验、API系统鉴定为金黄色葡萄球菌。

Methicillin-resistant strains ( MRSA and MRCNS) accounted for 65.3% of S.aureus ( SA) and 70.7% of coagulase-negative staphylococci ( CNS) respectively. No vancomycin-resistant ( VRE) or-intermediate ( VIE) strains were found in staphylococcus isolates.

金黄色葡萄球菌（SA）和凝固酶阴性葡萄球菌（CNS）中甲氧西林耐药株（MRSA和MRCNS）各占65.3%和70.7%，未发现万古霉素耐药株和中介株。