copy number variation

The copy number variation that researchers had seen before was simply the tip of the iceberg, while the bulk lay submerged, undetected, said Dr Hurles.

研究人员以前看到的复制数量变化只是冰山一角，而其绝大部分都还未浮出水面，未被发现，赫尔斯博士说。

Objective: 1. To establish a Genomic Copy Number Variation Database of Growth and mental retardation. 2. To analyze the sequence features of Copy Number Variation in order to study their formation mechanism. Methods: 1.

目的：1、建立生长发育迟缓智力障碍全基因组拷贝数变异（CNV）数据库2、分析拷贝数变异序列特征，对其形成机制进行初步研究。

DEFB gene products are small antimicrobial proinflammatory peptides, and copy number variation ( CNV) could reasonably influence susceptibility to infection and inflammation.

DEFB基因产物是小分子抗菌肽，且拷贝数变化（CNV）可显著影响易感性及炎症反应。

The combination of copy number variation and gene expression signatures help to understanding of potential mechanisms involved in drug resistance.

拷贝数变异和基因表达的整合分析有助于理解化疗耐药性的潜在机制。

Sequence and Copy Number Variation of Oleate Desaturase Gene ( FAD2) in Brassica Species

芸薹属作物油酸脱饱和酶基因（FAD2）拷贝数和序列变异分析

Genome-wide Copy Number Variation Study Associated with Obesity in Chinese Population

中国人群肥胖与全基因组拷贝数变异关联研究

All of the CGHT sufferers had a copy number variation in which DNA was deleted across the same four genes, the authors report today in the American Journal of Human Genetics.

研究人员在今天出版的《美国人类遗传学杂志》上报道：所有的CGHT患者都存在拷贝数变异现象，在相同的四个基因里都存在DNA缺失。

Copy-number variation: a new pattern of structural diversity in genome

拷贝数变异：基因组多样性的新形式

Established the Genomic Copy Number Variation Database of Growth and mental retardation.

结论：1、构建了生长发育迟缓智力障碍全基因组拷贝数变异（CNV）数据库。

A gene regulation network was then built to further identify genes responsible for differential gene expression and copy number variation between the chemotherapy resistant group and the chemotherapy sensitive group.

然后建一个基因调控网络进一步查明负责化疗耐药组和化疗敏感组之间的差异表达基因的拷贝数变异的基因。

Through the copy number variation analysis, regions possible related to Cri-du-chat Syndrome and Pierre Robin Sequence were identified. 2.

通过拷贝数变异分析为猫叫综合征及Pierre Robin序列征提供了可能相关区域。