cyclooxygenase

QSAR analysis of cyclooxygenase inhibitor using gene expression programming

基因表达式编程在环氧酶抑制剂定量构效关系中的应用

Conclusions Butyrates and NSAIDs could induce apoptosis individually. Combination with the two drugs could enhance the above effects by down regulating cyclooxygenase 2 expression.

结论单用丁酸盐和2种NSAIDs制剂均有促凋亡作用，联用可通过下调环氧化酶2的表达进一步增强疗效。

For relief of mild to moderate pain; inhibits inflammatory reactions and pain by decreasing activity of cyclooxygenase, which results in decrease of prostaglandin synthesis.

缓解轻微到中等的疼痛，通过降低环氧合酶的的活性，阻止炎性反应和疼痛。降低环氧合酶可以降低前列腺素合成。

Effect of cyclooxygenase inhibitor on metabolic response in septic patients

环氧酶抑制剂对脓毒症患者代谢反应的影响

Study on synergistic cytotoxic effects and mechanism of selective cyclooxygenase-2 inhibitor and cisplatin against human lung cancer cell lines

选择性COX-2抑制剂联合顺铂对肺癌的协同细胞毒作用及其机制研究

Garlic-derived Diallyl Disulfide ( DADS) Suppresses the Tumor Cell Phenotype and Transcriptional Expression of Cyclooxygenase-2 in Human Breast Cancer MDA-MB-231 Cells

大蒜成分DADS抑制人类乳腺癌细胞MDA-MB-231的恶性表型及环氧化酶-2的基因表达

Antitumor effects of specific cyclooxygenase inhibitors combined with chemotherapeutic agents on gastric cancer cells in vitro

特异性环氧合酶抑制剂和抗癌药联用对胃癌细胞增殖的影响

Protective effects of specific cyclooxygenase-2 inhibition in the treatment of MRL/ lpr mice

特异性环氧化酶-2抑制剂对MRL/lpr小鼠狼疮性肾炎的治疗作用

Objective To study the cyclooxygenase-1 ( COX-1) and cyclooxygenase-2 ( COX-2) messenger RNA ( mRNA) expression in rat brain tissue of ischemia/ reperfusion.

目的研究比较脑缺血及再灌注期环加氧酶异形体（COX-1和COX-2）基因的表达及其意义。

Progress in research on cyclooxygenase 2 in evolution of breast cancer

环氧化酶-2在乳腺癌演变过程中的作用研究进展

Effect of Bushen Huoxue decoction on expression of cyclooxygenase-1 mRNA in PCO rats

补肾活血方对PCO大鼠卵巢COX-1mRNA表达的影响

The effect of simultaneously blocking target epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2 on the growth of NPC cell

靶向联合阻断表皮生长因子受体和环氧化酶-2信号通路影响鼻咽癌细胞生长的研究

Effect exerted by Panax notoginseng saponins during lung ischemia reperfusion injury upon cyclooxygenase-2 and its genetic expression

三七总皂甙对肺缺血再灌注时环氧酶-2及其基因表达的影响

Expression of cyclooxygenase 2 following ischemic middle cerebral artery in rat

大鼠大脑中动脉缺血后环氧合酶-2表达的研究

Inhibitory effect of blocking both epidermal growth factor receptor and cyclooxygenase-2 pathway on proliferation of lung cancer A549 cells

阻断表皮生长因子受体和环氧合酶-2信号途径对肺腺癌细胞的抗增殖作用

Expression and Significance of Cyclooxygenase-2 in Focal Ischaemic Model of Middle Cerebral Artery in Rats

大鼠大脑中动脉局灶脑缺血环氧酶2蛋白的表达及其意义

Research on the Role and the Clinical Significance of Cyclooxygenase in Prostate Cancer

环氧化酶与前列腺癌的关系及其临床意义的研究

Aim: To observe the changes of cyclooxygenase-2 ( COX-2) expression and especially the time course of the changes in dorsal horn of the spinal cord during formalin-induced inflammatory pain and hyperalgesia in rats.

目的：观察甲醛炎性痛及痛过敏过程中脊髓后角环氧化酶2（COX2）表达的变化及其时间特征。

Objective To study the expression of cyclooxygenase-2 (COX-2) and HER-2 in human breast cancer and their relationship.

目的研究环氧化酶2 (COX 2)和表皮生长因子2 (HER 2)在乳腺癌中的表达及其相关性。

Three dimensional quantitative structure activity relationship of selective cyclooxygenase 2 inhibitors

选择性环氧合酶-2抑制剂的三维定量构效研究

Background and Aims: Cyclooxygenase ( COX) is a key enzyme in the synthesis of prostaglandins ( PGs) and thromboxanes ( TXs).

环氧化酶（cyclooxygenase，COX）是前列腺素和血栓素合成的关键酶。COX有两种异构体：COX-1和COX-2。

Because NSAIDs indiscriminately inhibit both isoforms of cyclooxygenase ( COX), they are frequently associated with severe adverse effect such as gastric perforation, gastrorrhagia, ulcers, when they are showing therapeutic efficacy.

由于NSAIDs对两种环氧合酶（COX）的抑制没有选择性导致其在发挥疗效时常伴有严重的副反应，例如胃穿孔、胃出血、溃疡等。

Conclutions: Effect of aromatase inhibitor in combination with cyclooxygenase-2 inhibitor on endometriotic explants of rat models proved obvious, and it was slightly superior to that of aromatase inhibitor alone.

结论：芳香化酶抑制剂联合环氧合酶-2抑制剂对大鼠内异症异位内膜的作用略优于单用芳香化酶抑制剂；

AMG is a non-selective cyclooxygenase ( COX ) inhibitor and could inhibIt'synthesis of prostaglandins ( PGs ).

AMG是非选择环氧化酶 ( Cyclooxygenase,COX ) 抑制剂,通过抑制前列腺素 ( Prostaglandins, PGs ) 合成发挥较强抗炎镇痛作用.

The Influence of the Acidic Components of Aubergine Root to Cyclooxygenase-2

茄根酸性组分对环氧化酶-2的影响

Cyclooxygenase ( COX), also called prostaglandin peroxidate synthetase, is rate-limiting enzyme which catalyses arachidonic acid synthesizing endogenous prostaglandin, including three types of isomeride.

环氧化酶（cyclooxygenase，COX）又称前列腺素过氧化物合成酶，是催化花生四烯酸合成内源性前列腺素的限速酶，包括3种同分异构体。

Background& Objectives: Cyclooxygenase ( COX) is a rate limiting enzyme in prostaglandin synthesis.

背景与目的：环氧化酶（cyclooxygenase，COX）是人体内合成前列腺素的限速酶。

Besides cyclooxygenase and nitric oxide synthase, another distinct endothelial pathway, endothelium-dependent hyperpolarization factor ( EDHF), is involved in relaxation of the vascular smooth muscle cells.

内皮依赖性超极化因子（endothelium-depen-denthyperpolarizingfactor，EDHF）是血管平滑肌内皮源性舒张反应中通过非环氧合酶、非一氧化氮合酶途径的舒张因子。

Objective To reveal the relations between expression of cyclooxygenase-2 ( COX-2) and tumor biological behavior and implications in tongue squamous cell carcinoma ( TSCC).

目的探讨环氧化酶2（COX2）的表达与舌鳞癌生物学行为的关系及意义。

Inhibition of cyclooxygenase 2 synthesis suppresses Herpes simplex virus type 1 reactivation

环氧化酶-2抑制剂对Ⅰ型单纯疱疹病毒复活的抑制作用