excision repair

Nucleotide excision repair ( NER) mechanism is essential for the maintenance of organism genome integrity.

核苷酸剪切修复（NER）途径是维持生物体基因组稳定的重要机制。

The primary function of which is the base excision repair ( Base excision repair, BER) process, playing an important part in filling the single nucleotide gap.

其主要功能是碱基切除修复（base excision repair，BER），在单核苷酸缺口的填补中起重要作用。

APE1/ Ref-1 plays a central role in DNA base excision repair, redox-dependeent regulation of specific transcriptional factors and production control of reactive oxygen species.

它在DNA的碱基切除修复、对转录因子的氧化还原调控和活性氧簇的调控等多个重要的生物学过程中发挥着主要的作用。

There are complete repair system in normal cells, including base excision repair system ( BER) and homologous recombination repair system ( HR).

人类细胞内存在着完整的修复系统，其中包括碱基切除修复系统（base excision repair，BER）和同源重组修复系统（Homologous Recombination，HR）。

The relationship between the DNA excision repair ability and the content of non-histone nuclear proteins of male germ cells of dog and rat

狗及大鼠精巢细胞的PNA切除修复能力与其核内非组蛋白含量的关系

Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

There are many DNA repair pathways to different DNA lesions, including base excision repair, nucleotide excision repair, mismatch repair and homologous recombination repair.

针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复，包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。

A special target of the granzyme A cell death pathway is an endoplasmic reticulum-associated complex, called the SET complex, which contains three granzyme A substrates, the nucleosome assembly protein SET, the DNA-binding protein HMG-2, and the base excision repair endonuclease Apel.

GzmA靶向作用于一种与内质网结合的特殊的复合体&SET复合体，其包含3种GzmA底物：核小体装配蛋白SET、DNA结合蛋白HMG-2、具有碱基切除修复作用的核酸内切酶Apel。

The DNA oxidative damage is believed that it is repaired mainly by the base excision repair ( BER) mechanism with many repairing enzymes.

已知细胞中DNA氧化性损伤主要通过碱基切除修复（BER）来完成，许多修复酶参与了这一修复过程。

Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining.

目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径，包括碱基切除修复、同源重组修复和非同源末端重接。

Genes encoding enzymes involved in DNA replication are potential targets for mutations leading to cancer. Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

碱基切除修复（BER），是清除细胞内DNA损伤的主要途径。碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

Objective Redox factor 1 ( ref-1), also known as AP endonuclease ( APE), is one of the very important components of DNA base excision repair and redox.

目的氧化/还原因子1（ref1），也称为AP核酸内切酶（APE），是氧化还原和DNA碱基切除修复途径中的重要一员。

Effect of benzopyrene on DNA damage and expression of genes involved in nucleotide excision repair in lung cancer cells

苯并（a）芘对肺癌细胞DNA损伤及修复基因表达水平的影响

At the first five days of the recovery period, the increased DNA damage may be due to the repair of DNA damage, such as base or nucleotide excision repair.

在恢复阶段的早期5天内，DNA损伤持续的增加，这应该是由于对DNA损伤的修复造成的，例如，碱基切除修复或者核苷酸切除修复。

BACKGROUND& OBJECTIVE: Xeroderma pigmentosum group C ( XPC) gene is involved in nucleotide excision repair ( NER).

背景与目的：XPC基因参与核苷酸切除修复，该基因存在单核苷酸多态性（SNP）位点，并可能通过SNP位点碱基的改变影响其修复能力及疾病易感性。

Nucleotide excision repair ( NER) can recognize a broad spectrum of helix-distorting lesions and is a major repair system of DNA damage.

在DNA损伤的众多修复途径中，核苷酸切除修复（NER）途径能广谱识别大多数严重损伤造成的DNA螺旋扭曲，是DNA损伤的主要修复系统，也是机体抵抗致癌效应的主要防御机制。

Expression of DNA polymerase β induced by all-trans retinoic acid and dimethyl sulfoxide and change of the base excision repair in human esophageal cancer cells

诱导分化的人食管癌细胞DNA聚合酶β和碱基切除修复功能的改变

Polymorphisms in nucleotide excision repair genes XPC and XPD and clinical responses to platinum-based chemotherapy in advanced non-small cell lung cancer

XPC和XPD基因遗传多态与晚期非小细胞肺癌对铂类药的敏感性

This is particularly important for Mycobacterium tuberculosis and other intracellular pathogens, fpg is the key enzyme in base excision repair.

碱基切除修复对结核分枝杆菌等胞内致病菌尤其重要。fpg是碱基切除修复的关键酶。

Objective To investigate the association of polymorphisms of nucleotide excision repair genes and chromosomal damage in peripheral blood lymphocytes among coke-oven workers.

目的研究核苷酸剪切修复酶基因多态性与焦炉作业工人外周血淋巴细胞染色体损伤易感性的关系。

DNA polymerase B ( pol B) is the key enzyme for single base excision repair.

DNA聚合酶β（polymeraseβ，polβ）主要是单个碱基切除修复中的关键酶之一。