gene knockout

The existing problems were analyzed and the development trend of gene knockout was discussed.

分析存在的问题并展望了相关技术诸多领域的发展趋势。

Establishment of a β B2 crystallin gene knockout mice model

βB2晶体蛋白基因敲除小鼠模型的建立

The Advances in the Research of Gene Knockout Mice

基因剔除小鼠研究的新进展

Generation of a Gene Knockout Mouse by Using a Gene Trap Strategy

利用基因诱捕技术进行小鼠基因剔除的初步研究

Gene Knockout Model and New Drug Target Discovery

基因敲除模型与药物作用新靶点的发现

In pathological conditions like diabetes, iNOS gene knockout help the recovery of abnormal glucose tolerance.

在类似糖尿病的病理条件下，iNOS基因的敲除有助于恢复糖耐量的异常。

Gene knockout offers an possibility to study the function of a particular gene in mice.

基因敲除技术为在小鼠体内研究某一特定基因的功能提供了可能。

Status Quo and Application of Gene Knockout

基因敲除技术现状及应用

In addition, the techniques such as hit and run, double replacement, tag and exchange and recombinase-mediated cassette exchange all contribute to the development of gene knockout technology.

此外，进退策略、双置换法、标记和交换法、重组酶介导的盒子交换法也从不同方向发展了基因敲除技术。

The principle and experimental practice of gene knockout

基因打靶技术的原理及操作

Gene knockout mice are often used to study genic functions.

基因敲除技术是研究基因功能的常用方法。

Genome Editing is a a new technology to transform biological genome based on gene targeting modified, through Precise gene editing in the genomic level, we can achieve the purpose of gene knockout and knockin structural variation.

基因组编辑是建立在基因靶向修饰的基础上，对生物基因组进行改造的一项新技术，通过在基因组水平上进行精确的基因编辑，实现基因的敲除、敲入、结构变异。

Lipid metabolism in lipoprotein lipase gene knockout heterozygous mice

脂蛋白脂肪酶基因敲除小鼠脂代谢动态观察

Application of Gene Knockout and Gene Defect Models in the Study of Drug Membrane Transport

基因敲除与基因突变动物模型在药物跨膜转运研究中的应用

Study on Gene Knockout Using Red System in Shigella flexneri

Red重组系统在痢疾杆菌基因敲除中的应用研究

Study on Several key Techniques in Establishment of Gene Knockout Mouse Production

基因剔除小鼠制作过程中相关技术的建立

Conclusion: The results shows that no significant alteration on glycometabolism or bone metabolism was found in APN gene knockout mice.

结论：脂联素基因剔除小鼠在基础状态下并无显著的糖代谢和骨代谢异常。

Molecular techniques such as gene knockout partially support the monoamine theory of depression.

诸如基因部分敲除的分子技术支持抑郁症的单胺理论.

AIM: To compare serum tumor necrosis factor α( TNF α) concentration in liver specific glucokinase gene knockout mice and two kinds of streptozotocin induced diabetic mice, and to explore the possible role of TNF α in the pathogenesis of diabetes mellitus.

目的：通过比较肝脏特异性葡萄糖激酶基因敲除小鼠和两种链脲菌素诱导的糖尿病小鼠模型血清肿瘤坏死因子α（TNFα）水平，初步探讨TNFα在糖尿病发病过程中的作用。