grignard

The former and 2,7-dibromo-fluorene, 2-bromofluorene were 9-oxidation, and then we attained six 9,9-diaryl-fluorene-based compounds by Grignard reaction and Friedel-Crafts reaction.

后者与2,7-二溴芴、2-溴芴作为起始化合物，分别经过9-位氧化、Grignard反应和Friedel-Crafts烷基化反应三步反应得到六个9,9-二芳基芴化合物。

Synthesis of Aromatics by Grignard Reaction with Supersonic Wave as Revulsant

超声波引发格氏反应制备几种香料

The very important pharmaceutical intermediate p-fluoro-α-methylstyrene was synthesized using fluorobenzene, bromine and acetone as raw materials via bromination, Grignard reaction and dehydration.

以氟苯、溴和丙酮为原料，通过溴代反应、Grignard反应，再经脱水反应制得医药中间体对氟α-甲基苯乙烯。

Preparation of highly reactive solvated metal magnesium atoms via metal vapor synthesis and preparation of Grignard reagent

金属蒸气合成法制备高活性的溶剂化金属镁原子及格氏试剂

Cross-coupling reaction of Grignard reagent catalyzed by nickel chloride

二氯化镍对格氏试剂交叉偶联反应的催化作用

Explore the new craft of preparing Grignard reagents.

探索合成格利雅试剂的新工艺.

Study the technologic conditions of preparing Grignard reagent benzylmagnesium chloride under ultrasonic condition.

研究超声波法制备格利雅试剂氯化苄基镁的工艺条件.

METHODS: With dehydroepiandrosterone 3 acetate as the raw material, the reactions included grignard reaction, hydrolysis, oppenauer oxidation and dehydrogen by DDQ ( 2,3 dichloro 5,6 dicyanobenzoquinone).

方法：以去氢表雄酮醋酸酯为原料，经格氏反应，水解，沃氏氧化，DDQ脱氢等四步反应制得。

The results show that the solution of the novel complex can form via the rapid interaction of magnesium, alcohol and alkylogen. The selected alkylogen shall not react with magnesium in the mode of Grignard reaction.

结果表明：将镁、有机醇以及不与镁发生格式反应的卤代烷相互作用可迅速发生反应形成新型含镁络合物溶液。

△~ 6-6-methyl spirolactone(ⅷ) was synthesized from epoxide(ⅱ) through the following series of reaction, viz, Grignard synthesis with the introduction of 6-methyl and side chain carboxyl groups simultaneously, followed by catalytic hydrogenation, chromic acid oxidation, dehydration and dehydrogenation.

△~6-6-甲基螺甾内酯（Ⅷ）可从环氧化合物（Ⅱ）经Grignard试剂一步加入6-甲基及侧链羧基，继用常法氢化、氧化、脱水、脱氢等步骤合成。

The Grignard-like reaction was that used the reagent replaced magnesium with zincum in water.

类格氏反应是用锌代替镁，在水体系中进行的增长碳链的反应。

ResultsThe main by-product was11,17-d i-addition product of Grignard reagent of N, N-dimethylamino phenyl bromide.

结果证实了副产物是11，17位双加成的格氏反应的产物。

The thesis discusses the phenyl chlorine silane cleaner production technologies, and puts forward the synthesis of phenyl trichlorosilane technical route through the application Grignard reaction which can solve shortcomings of traditional methods, that is high energy consumption, more by-products, and environment pollution. 2.

文中论述了苯基氯硅烷的清洁生产工艺，提出了用格氏法合成苯基三氯硅烷的研发思路，从根本上解决传统方法能耗高、副产物多，环境污染的缺点。

Synthesis of 4-( N, N-Dimethylamino) butanal Diethyl Acetal by Grignard Reaction

格氏反应合成4-（N，N-二甲胺基）丁醛缩二乙醇

A Significant Pathway for the Reactions between Grignard Reagents and Ketones-Single Electron Transfer Process

格氏试剂与酮反应的一个重要途径&单电子转移

Tetraallylsilane was obtained by the action of the tetrachlorosilane on the allyl Grignard regent.

将四氯化硅与烯丙基格氏试剂作用来制备四烯丙基硅.

Through experiment we discussed the preparative condition and came out with methods of mono-Grignard Reagent preparation.

通过实验讨论了它们的制备条件,提出了 单格 氏试剂的两种制备方法.

The additionhydrolysis reaction of benzimidazolium salts with Grignard reagent nucleophiles was found and reported.

发现并报道了苯并咪唑盐与格利雅试剂等亲核试剂的加成-水解反应.

Grignard reaction of methyl pyropheophorbide substituted at 3-position by acyl group and synthesis of chlorophyll derivatives

3-酰基焦脱镁叶绿酸甲酯的格氏反应及其叶绿素衍生物的合成

At last, the 1,1,4,4-tetraphenyl-1,3-butadiene derivatives ( 3a) and ( 3b) were synthesized by the Grignard reaction of ( 2) and benzophenone derivatives, with the yields being higher than 54.0%. The synthesizing requirements of all the steps were studied.

再与二苯甲酮衍生物经格氏反应制得了1,1,4,4-四苯基-1,3-丁二烯衍生物（3a）和（3b），收率高于54.0%，并对各步合成的工艺条件进行了研究。

Cyclic amide ( incl. cyclic carbamates) and their derivatives ( excl. ureines and their derivatives), and salts thereof Grignard reaction of methyl pyropheophorbide substituted at 3-position by acyl group and synthesis of chlorophyll derivatives

环酰（包括环氨基甲酸酯）及其衍生物（不包括烷基脲及基衍生物）和它们的盐类3-酰基焦脱镁叶绿酸甲酯的格氏反应及其叶绿素衍生物的合成

Di-Grignard Reagent and mono Grignard Reagent were prepared using 1, 4-dibromobutane.

以1, 4- 二溴丁烷为原料,分别制备了双格氏试剂和单格氏试剂.

Studies on the Synthesis of Sesamin-group Lignans IV.A Study of the Reaction between Dimethyl 2-Phenyl-furane-3,4-dicarboxylate and Grignard Reagents

芝麻素类型木脂素的合成研究Ⅳ2－苯基呋喃3，4－二羧酸二甲脂与格氏试剂反应的研究

Two synthetic methods of organosilicon compounds were adapted. Comparing the merits and demerits of the two methods, we found that it is convenient to use Grignard reagent in the reaction in almost same yield.

采用两种方法对有机硅化合物的合成进行了初步的探索，并比较了两种合成方法的优缺点，发现在产率大致相同的条件下，格式试剂法的后处理比较方便。

The article summarizes the preparation. structure and chemical nature of Grignard reagent.

本文综述了格氏试剂的制备, 结构及其在有机化学中的应用.

Research on The Application of Modified BP Neural Networks Model in Grignard Reaction

格氏反应中改进BP神经网络模型的应用研究

Classic carbon-carbon bond-forming reactions such as Grignard, Wittig, and Diels-Alder reactions have played significantly important roles in organic synthesis since their discoveries.

格氏反应、Wittig反应、Diels-Alder反应等经典的碳-碳键成键反应从它们的发现开始就在有机合成中扮演了举足轻重的角色。

After the Grignard reaction of ⅱ with ⅲ and the formation of hydrochloride salt, ⅳ was obtained by debenzylation in absolute ethanol with Pd/ C as catalyst under atmospheric pressure of hydrogen at 60 ℃ followed by hydrolysis with NaOH.

与进行格氏反应后，盐酸成盐，以无水乙醇作溶剂，5%Pd/C为催化剂，常压下60℃进行氢化脱苄，碱化后，得。

In this paper, 8-allyl-8-hydroxytricyclo [ 5,2,1,0 2,6] decane was prepared from tricyclo [ 5,2,1,0 2,6] decane-8-one through Grignard reaction.

在这篇文章中，以三环[5,2,1,02,6]癸烷-8-酮为原料，通过格氏反应合成了8-烯丙基-8-羟基三环[5,2,1,02,6]癸烷。

In the preparation of grignard reagent from inert alkyl bromide, the difficulty of the initiation of the reaction, which reduces the yield, limits its further application.

惰性卤代芳香烃在格氏试剂反应中，由于反应引发困难导致反应收率降低，影响格氏试剂的进一步应用。