hyperpnea

objective to investigate the effects of endothelin antagonist, bosentan on bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs and to explore the effect of endothelin in the pathogenesis of exercise induced asthma ( e1a).

目的通过内皮素（ET）受体非肽类拮抗剂Bosentan对豚鼠等CO2过度通气模型影响的观察，探讨运动性哮喘的发病机制以及ET受体拮抗剂的治疗作用。

from the results obtained, it seemed likely that the hyperpnea induced by intravenous injection of ammonium chloride was duo to direct excitation of the respiratory center by increase in hydrogen ion concentration of the blood, and that the peripheral chemoreceptors played no significant role in this effect.

氯化铵所致的呼吸增强，可能主要是由于血浆中氢离子增加对呼吸中枢的直接刺激作用，外周化学感受器在这方面不起重大作用。