The results indicated that down-regulation of PP participated in the loss of cholinergic neuron, formation of NTFs and clinical cognition deficit. It played an important role in the pathogenesis of AD.

  • 本研究结果提示PP活性降低可能参与了神经元纤维缠结形成、胆碱能神经元功能及认知功能障碍,在AD发病机制中起重要作用。

  • 互联网摘选 2026-07-13 00:31:26

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