METHODS Starting from 2-amino-5-methyl-pyridine, the key intermidiate 5-methyl-2 ( 1H) pyridone was obtained via the way of diazotization, hydrolysis, then it was aromatized with iodobenzene to give pirfenidone.

  • 方法以2-氨基-5-甲基吡啶为起始原料,经重氮化、水解得到关键中间体5-甲基-2(1H)吡啶酮,再与碘苯反应得到吡非尼酮。

  • 互联网摘选 2026-07-13 01:08:52

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