lovastatin

Cloning and Expression of Lovastatin Synthesis Regulatory Genes lovE and mkH

洛伐他汀合成调控基因LovE/mkH的克隆与表达

Lipid-Regulating Effects of Low Dose of Lovastatin and Simvastatin

小剂量洛伐他汀和辛伐他汀的调脂作用

Determination of two components in lovastatin and niacin sustained release tablets by HPLC

HPLC测定洛伐他汀烟酸缓释片中两组分含量

Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

方法: 以洛伐他汀为原料,通过酰化 、 甲基化 、 水解、环合等反应合成了辛伐他汀.

Optimization of formula of fermentation medium of lovastatin by uniform design

洛伐他汀发酵培养基配方的均匀设计优选

Objective To prepare the lovastatin and niacin sustained-release double-layer tablets and compare the sustained-release action of the abroad and homemade HPMC.

目的分别采用进口与国产羟丙基甲基纤维素（HPMC）作为骨架材料制备洛伐烟酸缓释双层片，并比较国内外HPMC的缓释作用。

Objective To review the advances on lovastatin fermentation by Aspergillus terrus.

目的综述土曲霉洛伐他汀发酵研究的进展.

Effect of lovastatin on the expression of I κ B α and cell-cycle regulating protein in MCF-7 cells

洛伐他汀对MCF-7细胞核转录因子和细胞周期调控蛋白表达的影响

It can be synthesized with the material of lovastatin, hydroxy protecting agent of trimethylchlorosilane, and t-butyl lithium instead of pyrrole lithium. The total yield is about 78%.

以洛伐他汀为原料，三甲基氯硅烷为羟基保护基，用活泼的强亲核试剂叔丁基锂代替当前的吡咯烷锂合成了目标产物新伐他汀，总收率达78%。

The efficacy of lovastatin and omega-3 fatty acid in treatment of combined hyperlipidemia in old people

洛伐他汀与Omega-3脂肪酸对老年混合型高脂血症患者的影响

Comparison Between Two Methods of determining content of Lovastatin Capsule

洛伐他汀胶囊的人体相对生物利用度洛伐他汀胶囊含量测定方法比较

Lovastatin is a potent cholesterol-lowering drug. This fungal secondary metabolite and its derivatives act as competitive inhibitors of HMG-CoA reductase, the rate limiting enzyme in the biosynthesis of cholesterol.

洛伐他汀是一种有效的降胆固醇药物，这种真菌次生代谢产物及其衍生物是胆固醇生物合成限速酶&HMG CoA还原酶的竞争性抑制剂。

Studies on Extended-Release Tablets of Niacin and Lovastatin Compound

复方烟酸和洛伐他汀缓释片的研究

Objective To construct one of yield lovastatin strain that is a very valid medicine for cholesterol-lowering.

目的探索构建洛伐他汀高产菌株的原生质体制备和融合方法.

Objective To evaluate the efficacy and safety of domestic lovastatin.

目的评价国产洛伐他汀的疗效和安全性。

Study on Release Determination Method of Lovastatin Sustained-release Tablets in Vitro

洛伐他汀缓释片体外药物释放度测定方法的研究