repair base

Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

The primary function of which is the base excision repair ( Base excision repair, BER) process, playing an important part in filling the single nucleotide gap.

其主要功能是碱基切除修复（base excision repair，BER），在单核苷酸缺口的填补中起重要作用。

APE1/ Ref-1 plays a central role in DNA base excision repair, redox-dependeent regulation of specific transcriptional factors and production control of reactive oxygen species.

它在DNA的碱基切除修复、对转录因子的氧化还原调控和活性氧簇的调控等多个重要的生物学过程中发挥着主要的作用。

There are complete repair system in normal cells, including base excision repair system ( BER) and homologous recombination repair system ( HR).

人类细胞内存在着完整的修复系统，其中包括碱基切除修复系统（base excision repair，BER）和同源重组修复系统（Homologous Recombination，HR）。

At the first five days of the recovery period, the increased DNA damage may be due to the repair of DNA damage, such as base or nucleotide excision repair.

在恢复阶段的早期5天内，DNA损伤持续的增加，这应该是由于对DNA损伤的修复造成的，例如，碱基切除修复或者核苷酸切除修复。

Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining.

目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径，包括碱基切除修复、同源重组修复和非同源末端重接。

There are many DNA repair pathways to different DNA lesions, including base excision repair, nucleotide excision repair, mismatch repair and homologous recombination repair.

针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复，包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。

The DNA oxidative damage is believed that it is repaired mainly by the base excision repair ( BER) mechanism with many repairing enzymes.

已知细胞中DNA氧化性损伤主要通过碱基切除修复（BER）来完成，许多修复酶参与了这一修复过程。

DNA polymerase B ( pol B) is the key enzyme for single base excision repair.

DNA聚合酶β（polymeraseβ，polβ）主要是单个碱基切除修复中的关键酶之一。

This is particularly important for Mycobacterium tuberculosis and other intracellular pathogens, fpg is the key enzyme in base excision repair.

碱基切除修复对结核分枝杆菌等胞内致病菌尤其重要。fpg是碱基切除修复的关键酶。