rosiglitazone

As one of sensitizing agents , rosiglitazone is mainly used to cure type 2 diabetes mellitus.

国外十余年的临床应用发现,罗格列酮可明显改善2型糖尿病病人的血脂紊乱, 延缓动脉粥样硬化病变进展.

Effect of rosiglitazone on the activity of hepatic nuclear factor-kappa B and expression of peroxisome proliferator-activated receptor-γ in mice with liver fibrosis due to schistosoma japonicum infection

罗格列酮对日本血吸虫病肝纤维化小鼠肝组织核因子-κB和过氧化物酶体增殖物激活受体γ表达的影响

spectrophotometric method for determination of the content of rosiglitazone maleate with bromophenol blue

溴酚蓝光度法测定马来酸罗格列酮的含量

Effects of Rosiglitazone on the Activities of AMPK in Skeletal Muscle of High-fat Fed Rats

罗格列酮对高脂饲养大鼠骨骼肌AMPK活性的影响

[ Conclusion] Repaglinide may improve the early insulin release, but full recovery of the phase peak amplitude is difficult, the therapeutic alliance of Repaglinide and Rosiglitazone may recover the early insulin release and PBG may be better controled.

【结论】瑞格列奈可改善胰岛素早期分泌时相，但恢复时相峰值困难，瑞格列奈与罗格列奈联合治疗可使2型糖尿病胰岛素早期分泌相恢复，餐后血糖控制更好。

OBJECTIVE To observe the effect of rosiglitazone maleate on insulin sensitizing and blood lipid level of diabetic rats induced by streptozotocin.

目的观察罗格列酮对由链脲霉素引起的2型糖尿病大鼠模型的血清胰岛素、肝细胞胰岛素受体及血糖的影响。

AIM: To investigate the effect of rosiglitazone on the binding activity of hepatic nuclear factor-kappa B ( NF-κ B) and the expression of peroxisome proliferator-activated receptor gamma ( PPAR γ) in mice with liver fibrosis caused by schistosoma japonicum infection.

目的：观察日本血吸虫病肝纤维化小鼠肝脏肝组织核因子-κB（NF-κB）的活性和过氧化物酶体增殖物激活受体γ（PPARγ）的表达，及PPARγ配体罗格列酮对其表达的影响。

Automatic clinical chemistry techniques could be employed to compare the glycemic and lipid effects of Pioglitazone and Rosiglitazone in animal models of non-insulin-dependent diabetes mellitus ( NIDDM).

自动生化分析技术可以作为一种有效的工具来比较罗格列酮和吡格列酮在非胰岛素依赖型糖尿病动物模型上的降糖和降脂作用。

Effects of rosiglitazone coadministration with compound sulfamethoxazole on the pharmacokinetics

与复方新诺明合用对罗格列酮代谢的影响

Methods: Twenty-five patients with PCOS plus insulin resistance were treated with rosiglitazone for 12 weeks.

方法25例PCOS合并胰岛素抵抗患者于自然月经或撤退性出血第5天服用罗格列酮12周，观察治疗前后血清生殖激素、胰岛素、血糖、血脂水平及排卵功能的变化。

Objective To study the effect of rosiglitazone on TNF α and IL-6 in patients with unstable angina pectoris ( UA).

目的探讨罗格列酮对不稳定性心绞痛（UA）患者血清IL-6、TNF-α的影响。

objective to investigate the effect of rosiglitazone and reduced glutathione on insulin signaling proteins in rats with nonalcoholic fatty liver disease ( nafld). methods nafld rats were produced.

目的研究罗格列酮联合还原型谷胱甘肽对非酒精性脂肪性肝病（NAFLD）大鼠胰岛素以及胰岛素信号转导相关蛋白表达的影响。

The HF+ RSG group added rosiglitazone by gastric gavage, mice in the other two groups were administered with physiologic saline of the same volume.

罗格列酮干预组增加罗格列酮灌胃，其余两组给予等量生理盐水。

Those three drugs share the same actie ingredient : rosiglitazone.

这三种药物的有效成分均含有罗格列酮.

Conclusions Rosiglitazone can reduce BP, improve insulin resistance and correct the abnormity of sugar and lipid metabolism.

结果提示，罗格列酮能降低X综合症大鼠的血压，减轻胰岛素抵抗，纠正糖、脂代谢紊乱。

" Healthcare providers and patients must be enrolled in the Avandia-Rosiglitazone Medicines Access Program in order to prescribe and receive rosiglitazone medicines," the FDA statement says.

FDA声明，医疗服务提供者和患者必须纳入文迪雅-罗格列酮药品方问计划，以处方和接收罗格列酮。

Rosiglitazone is a peroxisome proliferator-activated receptor γ( PPAR γ) agonists, which can induce apoptosis in non-small cell lung cancer and inhibit non-small cell lung cancer cell invasion and metastasis.

罗格列酮是过氧化物酶体增殖激活受体γ（PPARγ）激动剂，它能够诱导非小细胞肺癌凋亡并抑制非小细胞肺癌细胞侵袭及转移。

effects of rosiglitazone on the expression of atp-binding cassette transporter a1 in monocytes of coronary heart disease

罗格列酮对冠心病患者外周血单核细胞三磷酸腺苷结合盒转运子A1表达的影响

effects of rosiglitazone on the activity of cytochrome p450 3a in rat liver

罗格列酮对大鼠肝细胞色素P4503A活性的影响

Rosiglitazone belongs to a class of drugs known as peroxisome proliferator-actiated receptor ( PPAR ) agonists.

罗格列酮属于称为过氧化物酶体活化受体 ( PPAR )促效剂一类药物.

Determination of Rosiglitazone in Compound Rosiglitazone Metformin Tablet by HPLC-ketoglutarate pathway

HPLC法测定复方罗格列酮盐酸二甲双胍片中罗格列酮的含量α－酮戊二酸途径α

as exercise, diet, metformin and rosiglitazone that activate the "metabolic master switch" amp-activated protein kinase ( ampk), increase lipid oxidation and decrease the ectopic accumulation of lipid, which prevent or delay the onset of type 2 diabetes.

运动，饮食控制及激活代谢总开关一磷酸腺苷活化蛋白激酶（AMPK）的药物，二甲双胍、罗格列酮可促进外周组织的脂质氧化，降低脂质的异位堆积，阻止或延缓2型糖尿病的发生。

To observe the effects of Rosiglitazone on endothelial function in ASO patients.

观察罗格列酮对ASO患者外周血管内皮功能的影响.

Results 30 days later, FPG, FINS and homeostasis model assessment of insulin resistance ( 5.68 ± 1.214. vs. 36 ± 0.91 P < 0.01) decreased significantly in rosiglitazone group.

结果罗格列酮组患者治疗30天后，FPG、FINS以及胰岛素抵抗指数明显降低（5.68±1.214.vs.36±0.91P

Aims: To investigate the effect of peroxisome proliferator-activated receptor ( PPAR)-r li-gand rosiglitazone on dextran sulfate sodium ( DSS)-induced colitis of mice.

目的：观察过氧化物酶体增生物激活受体（PPAR）-r配体罗格列酮治疗葡聚糖硫酸钠（DSS）诱导小鼠结肠炎的疗效。

study on the relevance of matrix metalloproteinase-9 and type 2 diabetic macroangiopathy and the clinic observation of rosiglitazone intervence treatment

外周血基质金属蛋白酶-9与2型糖尿病大血管病变的相关研究及罗格列酮干预治疗临床观察

Effects of rosiglitazone on proliferation and differentiation of HL-60 cell

罗格列酮抑制HL-60细胞增殖和诱导分化作用

The panel's "dispassionate" efforts to make the right decision about rosiglitazone highlight three tenets that could be used for future drug approval, Rosen argues.

Rosen说，委员会为了对罗格列酮作出正确裁决的“心平气和”的努力，强调了三个可用于今后药品审批的原则。

Clinical observation of curative effect of rosiglitazone to 2 type diabetes mellitus

胰岛素增敏剂罗格列酮治疗2型糖尿病的临床疗效观察