telomerase

Objective: Telomeres and telomerase are closely associated with cellular senescence and immortalization.

目的：端粒-端粒酶系统在细胞的衰老、永生化等过程中起着非常重要的作用。

Results: Telomerase is a reverse transcriptase comprised of many subunit.

结果端粒酶是一多亚基复合物,具有逆转录酶活性.

Telomerase is a ribonucleoprotein complex whose function is to add telomere repeats to chromosomal ends to make its stable and cell immortalization.

端粒酶是核糖核蛋白复合体，其丰要功能是增加染色体末端端粒的不断重复以维护它的稳定性和细胞的恶性增殖。

Objects To investigate the possible relationship between telomerase activity and development of cervical carcinoma.

目的探讨端粒酶活性与宫颈癌的相关性以及与其发生发展的关系.

Research on expression of human papillomavirus type 16 and telomerase in oral lesions

16型人乳头状瘤病毒DNA及端粒酶在口腔粘膜病变中的表达

Objective: Telomerase is a ribonucleoprotein complex that synthesizes telomeric DNA onto chromosome ends using its RNA component as template, enabling extension of cell lifespan and even immortalization.

目的：端粒酶是一种核糖核蛋白复合物，能以自身RNA成分为模板催化染色体末端端粒重复序列的延伸，使细胞得以持续增殖甚至永生化。

Abstract: Objective To investigate telomerase activity in patients with psoriasis.

文摘: 目的探讨银屑病的端粒酶活性表达情况.

Telomerase SiRNA inhibits KB cell growth in human oral cell squamous carcinoma

端粒酶SiRNA抑制人口腔鳞状细胞癌生长的研究

Telomerase activity was examined in these samples with telomeric repeat amplification protocol ( TRAP).

用端粒重复序列扩增法（TRAP）测定上述组织标本中的端粒酶活性。

The Study of the Immortalization of Human Bone Marrow Mesenchymal Stem Cells by Transducting Human Telomerase Reverse Transcriptase Gene

转导人端粒酶逆转录酶基因致人骨髓间充质干细胞永生化的研究

These iPS cells also show insufficient activation of endogenous pluripotent genes and telomerase genes.

这些iPS细胞中，内源基因和端粒酶也激活不足。

Methods: Thirty-four non-Hodgkin's lymphoma and 6 Hodgkin's diseases were examined for telomerase activity by means of telomeric repeat amplification protocol ( TRAP) assay based on PCR.

方法采用PCR TRAP方法检验34例非霍奇金淋巴瘤和6例霍奇金病的端粒酶活性。

Their research showed that cells age if telomerase telomeres are shortened.

他们的研究显示如果端粒缩小,细胞将老化.

The relation between telomerase activity and human papillomavirus infection in cervical cancer

宫颈癌组织端粒酶活性与HPV感染的关系

Telomerase is RNA dependent DNA polymerase, acts to synthesize DNA repeat fragment of telomeres, which is associated with immortalization of cells.

端粒酶是一种RNA依赖的DNA多聚酶，可以合成端粒DNA的重复片段与细胞永生化密切相关。

Immortalization of cultures derived from primary breast carcinoma by ectopic expression of human telomerase reverse transcriptase and its significance

端粒酶永生化原始乳腺癌组织来源细胞及其意义

The detection of telomerase may be helpful to gastric cancer early.

追踪端粒酶阳性的胃癌前病变患者有利于早期发现胃癌.

Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.

结论端粒缩短并激活端粒酶是涎腺肿瘤形成的重要因素.

Enhancement of Telomerase and NF-Kappa B Activation in Vincristine-resistant Human Gastric Cancer Cells; Research of FXR in increasing expression of SR-BI in hepatocyte

端粒酶和核因子-kappa b在胃癌细胞长春新碱耐药中的作用研究法尼酯X受体在增强胎肝细胞中对B类清道夫受体Ⅰ表达的研究

To her surprise, she found no correlation between telomerase and longevity.

她惊奇地发现,端粒酶与寿命并不存在相关性.

Telomerase system is the genetic name of telomerase and telomere.

端粒酶系统是端粒和端粒酶的总称.

Telomerase interferes with this record keeping.

端粒酶干扰这一记录过程.

Telomerase, a ribonucleoprotein enzyme, is a key component in maintaining the development of malignant tumor.

端粒酶激活与恶性肿瘤发生发展之间存在着密切的关系.

The Scientists scientists named the telomerase.

科学家将之命名为端粒酶.

Conclusion: Down-regulating the telomerase activity may be responsible for its anti-cancer mechanism.

结论: 下调肿瘤细胞的端粒酶活性,可能是半枝莲 抗肿瘤 的重要机制之一.

Objective To investigate telomerase activity in patients with psoriasis.

目的探讨银屑病的端粒酶活性表达情况.

Conclusion Telomerase is a tumor specific gene marker.

结论端粒酶是一种特异性的恶性肿瘤基因标志物.

Objective : To explore the relation between telomerase activity and tumor biology.

目的: 探讨端粒酶活性与肿瘤生物学关系.

Objective : To explorethe composition, struction and activity regulative mechanism of telomerase.

目的综述端粒酶的组成 、 结构及其活性调节机制.

Conclusions: One step RT PCR is a powerful method for detecting telomerase subunits.

结论：一步RT-PCR是检测端粒酶亚单位的有效方法。