telomeric

Expression of fibronectin gene in pancreas carcinoma Human Telomeric Protein

人粘连蛋白基因在胰腺癌中的表达

Specific Attachment of Telomeric DNA to Nuclear Matrix in Hela Cells

HeLa细胞染色体端粒DNA与核骨架的特异性结合

Objective: Telomerase is a ribonucleoprotein complex that synthesizes telomeric DNA onto chromosome ends using its RNA component as template, enabling extension of cell lifespan and even immortalization.

目的：端粒酶是一种核糖核蛋白复合物，能以自身RNA成分为模板催化染色体末端端粒重复序列的延伸，使细胞得以持续增殖甚至永生化。

Analysis of telomeric restriction fragment in gastric cancer and its premalignant lesions

胃癌及癌前组织端粒状态的分析

In vitro binding of p53 and telomeric repeat factor 2

端粒重复因子2与p53的体外结合

Advances in the regulation mechanism of the telomeric length

端粒长度调控机制的研究进展

The role of telomeric length alteration in salivary tumor transformation

端粒长度变化在涎腺肿瘤发生中的作用

Therefore, normal human cells lack telomerase activity, their telomeric DNA lengths decrease gradually with the increasing numbers of cell divisions, eventually telomeres shortening induce cellular replicative senescence.

因此正常人体细胞缺乏端粒酶活性，端粒DNA长度随细胞分裂次数增多逐渐缩短，最终引起细胞复制衰老。

Methods Telomerase activity in 28 specimens of cervical carcinoma, 6 specimens of cervical dysplasia and 10 specimens of normal cervical tissues were detected by PCR based sliver staining Telomeric repeat Amplification Protocal ( TRAP).

方法：采用PCR TRAP方法对28例宫颈癌组织，10例正常宫颈组织，6例宫颈不典型增生组织的端粒酶活性进行检测。

Construction of antisense human telomeric RNA retroviral vector and its inhibition on colorectal cancer cells

反义人类端粒酶RNA逆转录病毒载体构建及其对结直肠癌细胞的抑制作用

Study on the mutation of human telomeric repeat binding factor 1 gene in malignant hematopoietic cell lines

恶性血液病细胞株人端粒重复序列结合因子基因突变情况的研究

Detection of telomerase activity in breast carcinoma by silver-staining telomeric repeat amplification protocol

银染端粒重复扩增技术检测乳腺癌组织端粒酶活性的研究

Improvement& Application of Telomeric Repeat Amplification Protocol ( TRAP) and Research on Telomerase characteristic

端粒重复扩增程序（TRAP）的改进和应用以及端粒酶酶学性质研究

The molecular interaction between P53 and telomeric repeat binding protein 1 in vitro

P53与端粒重复序列结合蛋白质1的体外相互作用

Minute Chromosome Rearrangement Detected by Human Telomeric Band Painting Probes

应用端粒区带涂染探针检测染色体微小结构重排

Primary Study on Spectrophotometric Detection of Telomeric DNA with Catalytic Beacons

催化信标检测端粒DNA序列的初步研究

We report the identification of a splice donor mutation in a novel gene, which is the mouse ortholog of a newly discovered telomeric regulator.

我们报告了一个新基因左拼接剪接变异的证据，这个新基因是一个新发现的鼠同源基因端粒调节体。

Methods: The telomeric repeat amplification protocol ( TRAP ) combined with densitometry and clinical examination were performed in leukemia patients.

方法: 端粒重复扩增法结合吸光度测定及临床病例分析.

Construction and expression of telomeric repeat binding factor 2 small interfering RNA eukaryotic vector

TRF2小干扰RNA载体的构建及表达

Telomeric loss in head and neck squamous cell carcinomas

染色体端粒的缺失表达在头颈部磷癌的意义

The reverse transcriptase telomerase is able to maintain stable telomeric length and essential for the unlimited proliferation of tumor cells. Telomerase activity has been detected in 85-90% of human tumors and tumor-derived cell lines but not in most human somatic cells.

端粒酶表达于85%以上的肿瘤细胞中，能够维持细胞中端粒的长度，对永生化细胞的增殖具有重要作用，而在大多数人正常体细胞中却没有表达。

Preparation and characterization of monoclonal antibody against human telomeric repeat binding factor 1

抗人端粒重复序列结合因子（TRF1~（33-277））单克隆抗体的制备及生物学特性初步鉴定

Expression of telomerase reverse transcriptase and telomeric repeat binding factor 2 during rat myocardial development

端粒酶逆转录酶和端粒重复结合因子2在大鼠心肌细胞发育过程中的表达

Study on the genome structure of human telomeric repeat binding factor 1 and its pseudogenes

人端粒重复序列结合因子基因组和假基因研究

Methods: Thirty-four non-Hodgkin's lymphoma and 6 Hodgkin's diseases were examined for telomerase activity by means of telomeric repeat amplification protocol ( TRAP) assay based on PCR.

方法采用PCR TRAP方法检验34例非霍奇金淋巴瘤和6例霍奇金病的端粒酶活性。

Measurement of the Telomeric Length of Hemangioma and Embryonic Kidney Endothelium

血管瘤和人胚肾血管内皮细胞端粒长度测定

A quantitative method to measure telomerase activity by bioluminescence connected with telomeric repeat amplification protocol

端粒重复扩增生物发光分析法定量检测端粒酶活性

Detection of telomerase activity in human lung cancer by silver staining telomeric repeat amplification protocol

银染端粒重复序列扩增法检测肺癌端粒酶活性

A PCR based telomeric repeat amplification protocol ( TRAP) was used for assaying telomerase activity.

用端粒重复扩增（TRAP）PCR法测定细胞的端粒酶活性。

Comparison and observation on chromosome telomeric associations in human lung cancer

人肺癌染色体端粒联合的比较观察