triazole

Azoles are the largest class of antifungal agents in clinical use. 1,2,3-Triazole moieties are attractive connecting units, as they are stable to metabolic degradation and capable of hydrogen bonding, which can be favorable in binding of biomolecular targets and solubility.

唑类是临床上应用最广泛的抗菌药物。1,2,3-三氮唑由于其不容易被生物降解和容易形成氢键增加了其与生物大分子的结合能力，被作为一个极具吸引力的连接单元广泛应用。

Kinetics of the Nucleophilic Substitution of 3-Amino-1,2,4-Triazole with Picryl Chloride

3－氨基－1，2，4－三唑与苦基氯的亲核取代反应动力学研究

Metal and triazole/ tetrazole can be built mononuclear, binuclear and trinuclear complexes. Carboxylic acid ligands are introduced the M-triazole/ tetrazole system, leading to coordination polymers and supermolecular structures by different coordination modes and intermolecular interaction. 2.

金属与唑类配体可形成单核、双核、三核结构单元，羧酸类配体再通过不同的配位模式及分子间作用力将其连接成为配位聚合物及三维超分子结构。

We present here the crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121 in complex with the triazole drug fluconazole, revealing a new azole heme ligation mode.

我们提出了肺结核分支杆菌细胞色素P450CYP121与三氮唑类药物氟康唑的复合物的晶体结构，揭示了唑类与亚铁血红素新的结合模式。

Being one of triazole antifungal agents, fluconazole has becoming the treatment of choice for invasive candidiasis because of its biological availability and safety.

三唑类代表性药物氟康唑因具有良好的生物利用度和安全性，被广泛用于治疗侵袭性假丝酵母菌感染。

Azole and triazole drugs are cytochrome P 450 inhibitors widely used as fungal antibiotics and antimycobacterial actiity.

唑类和三氮唑类药物作为细胞色素P450抑制剂广泛被作为抗真菌药物和抗微生物药物使用.

Objective : To study the antifungal activity of the new triazole compounds against candida species.

目的: 研究一类新型的三氮唑化合物对念珠菌属真菌的抗真菌活性.

Each triazole group of fluconazole links two SBUs and the compound 9 exhibits a chain-like architecture with strong antiferromagnetism.

氟康唑中的每个三唑基连接两个单元格，磁性研究表明配合物9存在强的反铁磁性。

Studies on the Synthesis and Bioactivity of Novel 3-Carboxyl-1,2,4-Triazole Compounds Containing Thioamide

含硫代酰胺基的新型3-羧酸-1,2,4-三唑类化合物的合成与生物活性研究

Plant hormone activity of Schiff bases of triazole, thiadiazole and tetrazole

三氮唑，噻二唑和四唑席夫碱的植物激素活性

Nucleophilic substitution of 3-amino-1,2,4-triazole with picryl chloride is reported. The relevant intermediate was separated, its structure determined and the possible reaction mechanism suggested.

测定了3－氨基－1，2，4－三唑参与的亲核取代反应动力学，并对相应中间体进行了分离和结构测定，给出了相应的反应历程。

In this paper PAHMT chelating resin having symmetrical triazole AHMT as the function group was synthesized by means of macroporous polystyrene backbone and the structure of resin was characterized.

本文以大孔聚苯乙烯树脂为骨架合成了含有对称三唑AHMT功能基的螯合树脂PAHMT，并对其结构进行了表征；

The increasing of oxygen content in complexes have a significant influence on the thermal decomposition of mixture system, which approves that the idea adding carboxylic acid to the M/ triazole/ tetrazole system is reasonable for the combustion catalysis in double-base solid propellant.

配合物含氧量的增加对混合体系热分解的影响是明显的，通过将羧酸引入到Cu、Co、Ni/三唑、四唑体系来实现双基同体推进剂燃烧催化的思路合理。

Advances in research on therapeutic drug monitoring of triazole antifungal agents

三唑类抗真菌药物治疗药物监测的研究进展

study on the synthetic process of new type of antibacterial agent: linezolid and its analogs; synthesis and antifungal activity of novel triazole compounds

新型氮唑类化合物的合成及其抗真菌活性研究

Thioureas have been attached great importance because of their special biological activities. A series of novel thiourea derivatives 4a~ 4e and thiosemicarbazide derivatives 5a~ 5e were synthesized by addition reaction of 2-phenyl-1,2,3-triazole-4-formyl isothiocyanate ( 1) with substituted 2-amino benzothiazole and 2-hydrazino benzothiazole respectively.

利用2-苯基-1,2,3-三唑-4-甲酰基异硫氰酸酯与2-氨基取代苯并噻唑和2-肼基取代苯并噻唑的加成反应合成了一系列二取代硫脲和氨基硫脲衍生物。

Study on the Nucleophilic Substitution of 3-Aryl-5-Mercapto-1,2,4-Triazole

3-芳基-5-巯基-1.2.4-三唑的亲核取代反应研究

Including, thiabendazole, or mycophenolate triazole, Prochloraz amines, malathion, and so IPRODIONE.

其中包括多菌灵, 噻菌灵, 抑霉唑, 咪鲜胺, 马拉硫磷, 异菌脲等.

Organochlorine and triazole pesticide residues were stabile in processing of farm induce.

有机氯类、有机唑类农药较为稳定,加工操作很难得到较好的去除效果.

studies on synthesis, structure and biological activities of novel triazole compounds containing thioamide

含硫代酰胺新三唑类化合物的合成、结构表征及生物活性研究

Clinical Observation and Experimental Study of Treatment of Traditional Chinese Medicine on Tinea Pedis; Advances in research on therapeutic drug monitoring of triazole antifungal agents

抗真菌颗粒剂治疗足癣的临床观察和实验研究三唑类抗真菌药物治疗药物监测的研究进展

theoretical studies on the structures and properties of high-nitrogen heterocycle compounds: triazole and tetrazine derivatives

三唑和四嗪类高氮杂环化合物结构和性能的量子化学研究

Azole and triazole drugs are cytochrome P450 inhibitors widely used as fungal antibiotics and possessing potent antimycobacterial actiity.

唑类和三氮唑类药物作为细胞色素P450抑制剂广泛被作为抗真菌药物和抗微生物药物使用。