valproate

A comparative study of lithium carbonate combined with sodium valproate in the prevention of bipolar disorder

碳酸锂合并丙戊酸钠预防双相障碍复发的研究

optimized therapeutic scheme and individualized dosage of sodium valproate in patients with bipolar disorder sub-type ⅰ

丙戊酸钠治疗双相Ⅰ型障碍患者方案优化与实施个体化剂量的研究

Research group were given anti-psychotics combined with magnesium valproate, its beginning dosage was 400mg/ d and reached 800~ 1200mg/ d after one week, and control group with single anti-psychotics for 4 weeks.

研究组在原有抗精神病药治疗的同时加用丙戊酸镁治疗，起始剂量400mg·d-1,1w后增至800mg～1200mg·d-1；对照组继续原有抗精神病药治疗。

sodium valproate effectively protected against stage 5 seizures and shortened the afterdischarge duration.

丙戊酸钠抑制5期反应作用较强，并能显著缩短刺激后放电时程。

effect of sodium valproate on ectopic spontaneous discharge of injured dorsal root ganglion neurons in rats

丙戊酸钠对大鼠损伤背根节神经元异位自发放电的抑制作用

pharmacokinetics of sustained-release sodium valproate in 5 children with epilepsy

丙戊酸钠缓释片在5例癫痫儿童的药物动力学

a case of acute interstitial nephritis caused by sodium valproate is reported.

例急性间质性肾炎造成丙戊酸钠报道。

OBJECTIVE To establish the content determination method of sodium valproate tablets by capillary column gas chromatography.

目的建立高效毛细管气相色谱法测定丙戊酸钠片剂的含量.

effect of sodium valproate on bicuculline-induced epileptiform activity in rat hippocampal slices in vitro

丙戊酸钠对荷包牡丹碱诱发大鼠海马脑片痫样放电的影响

results: the rate effective cure for primary trigeminal neuralgia with sodium valproate was 79.5% and effective daily dose was 0.6~ 2.0g.

结果丙戊酸钠治疗原发性三叉神经痛的总有效率为79.5%，剂量为0.6～2.0g。

effects of sodium valproate on electrocardiographic changes and death time in rats

丙戊酸钠对小鼠心电改变及死亡时间的影响

monitoring of serum concentrations and the clinical significance on children treated with sodium valproate

丙戊酸钠治疗285例儿童癫痫病的血药浓度监测及其临床意义

The authors also found a dose-dependent relationship between valproate and IQ score.

作者也发现丙戊酸钠和IQ值之间的剂量依赖性关系.

a clinical contrast of curative effect of topiramate and sodium valproate in treatment of general tonic clonic seizure

托吡酯和丙戊酸钠治疗特发性全面性强直阵挛发作的临床疗效比较

clinical analysis of antiepileptic therapy with individuated-dose valproate in child

丙戊酸钠个体化剂量治疗癫痫的临床分析

Proliferation inhibition of sodium valproate on lung cancer cell line A549

丙戊酸钠抑制肺癌细胞株A549增殖的研究

As a first-line agent for treating epilepsy, valproate sodium is widely used in clinic.

丙戊酸钠作为常用一线抗癫痫药, 目前在临床的应用较为广泛.

postoperative clinical application of sodium valproate on brain tumors

丙戊酸钠在脑肿瘤术后的临床应用

AbstractObjectiveTo investigate the effects of valproate treatment on plasma insulin and leptin levels of epileptic children.

目的探讨丙戊酸治疗对癫疒间患儿血浆胰岛素和瘦素水平的影响.

objective: to study and compare the prophylactic efficacy of levetiracetam, valproate and phenobarbital on febrile convulsions in rats.

目的：比较左乙拉西坦、丙戊酸钠、苯巴比妥对大鼠反复热性惊厥的预防作用的差异，指导临床选药。

an analysis of the result from monitoring serum concentration of children with epilepsies treated with sodium valproate

丙戊酸钠治疗儿童癫痫的血药浓度监测结果分析

importance of monitoring of serum concentration of sodium valproate in epileptic children

血药浓度监测对丙戊酸钠治疗小儿癫痫的指导意义

effect of borneol on sodium valproate passing blood-brain barrier

冰片对丙戊酸钠透过血脑屏障的影响

RESULTS: Simple and complex partial seizures with or without secondary generalized seizure, in topiramate group were much more improved than these in sodium valproate group 6 mo after treatment.

结果：托吡酯组治疗6mo的继发性全身发作，简单及复杂性部分发作有效例数优于丙戊酸钠组，4例在加药期快时出现疲劳、嗜睡、注意力不集中等。

comparative proteomic analysis of differentially expressed proteins in hippocampus of developmental rats with mesial temporal lobe epilepsy following treatment with valproate

发育期大鼠内侧颞叶癫痫模型丙戊酸治疗前后的蛋白质组学研究

Clinical analysis of thrombocytopenic purpura caused by sodium valproate treatment in 8 children with epilepsy

丙戊酸钠致血小板减少性紫癜8例临床分析

Toddlers whose mothers had taken valproate IQs of 92, on average.

这些母亲服用抗癫痫药的小孩智商平均是92.

since 2004, prescriptions of carbamazepine, phenytoin and valproate decreased while levetiracetam increased.

从2004年，卡马西平、苯妥英和丙戊酸盐的剂量减少了然而左乙拉西坦的剂量增加了。

Objective To investigate the clinical efficacy and side effects of sodium valproate in the treatment of alcohol withdrawal reaction.

目的探讨丙戊酸钠对酒精戒断反应的临床疗效及副反应。

METHODS: Sodium valproate was administered by osmotic minipump technique ( 1. 062 mg · h-1) and iv ( 50 mg · kg-1) to ICR mice fed under ad lib or time-restricted schedules to determine the time-dependent changes of VA kinetics.

方法：对自由进食及限定进食的ICR小鼠分别以渗透压微泵技术（1.062mg·h~（-1））及iv（50mg·kg~（-1））给予丙戊酸钠，并测定VA动力学的时间依赖性变化。