histone的例句大全

Epigenetic variation plays an important role in plant growth and development, including DNA methylation, histone modification, chromosome remodeling, and RNA interference and so on.

表观遗传变异对于植物的生长发育起着重要作用，主要包括DNA甲基化、组蛋白修饰、染色体重塑和RNA干涉等。

DNA methylation is often interact with histone modification to regulate gene expression.

DNA甲基化往往与组蛋白修饰相互作用共同调控基因的表达。

Epigenetic modification includes DNA methylation and histone modifications.

表观遗传修饰主要有DNA甲基化和以组蛋白修饰为特征的染色质重塑。

Histone modifications plays an important role in transcriptional regulation. Histone modification enzymes, such as HATs, HDACs, HMTs control the chromatin structure and gene expression, thus participate in gene transcription regulation of specific sites.

组蛋白修饰在基因转录调控中占有重要地位，在组蛋白修饰酶HATs、HDACs、HMTs的共同作用下控制着染色质的结构和基因的表达，从而参与特定位点的基因转录调控。

AIMNESS: Histone modification as one of the key epigenetic regulation mechanisms plays critical roles in various biological processes, including regulation of chromatin structure dynamics and gene expression.

目的：组蛋白修饰在基因表达调控等多种生物学过程中起着重要作用，是表观遗传中重要的调控机制之一。

DNA hypomethylation, likely to be cooperating with aberrant histone modification, may induce the activation of some T cell genes and development of autoimmunity in SLE.

DNA的低甲基化可能在异常组蛋白修饰的协同下引起某些T细胞基因的异常活化，导致狼疮自身免疫的发生。

Aberrant DNA Methylation and Histone Modification in Tumor

肿瘤DNA异常甲基化与组蛋白修饰

Among various histone modifications identified, histone lysine methylation functions in virtually all chromatin based biological processes including transcriptional regulation and DNA damage repair.

在现有的多种组蛋白修饰中，组蛋白赖氨酸的甲基化实际上参与了所有的以染色质为基础的生物进程，包括转录调控和DNA损伤修复。

Objective To study the role of histone modification in the regulation of IFN-gamma-activated gene using chromatin immunoprecipitation technique.

目的应用染色质免疫沉淀技术研究组蛋白修饰与干扰素γ应答基因调控的关系。

Differential histone modification marks of active versus repressed genes accompany these DNA methylation changes.

活化的差异组蛋白修饰标记物对抑制基因的改变伴随着这些DNA甲基化改变。

The changes of epigenetics such as DNA methylation and histone modification can regulate the expression of genes and play an important role in the development of tumors.

表遗传学改变，如DNA甲基化和组蛋白修饰改变可以调节基因的表达，在肿瘤的发生和发展中可能起关键作用。

Epigenetics refers to gene expression changes which DNA sequence will not changed, the main contents of epigenetic mechanism is that DNA methylation and histone modification.

表观遗传学指不发生DNA序列改变的基因表达改变，DNA甲基化和组蛋白修饰是其中的两个主要内容。

In the paternal or maternal alcohol exposure during pregnancy, parents with alcohol intake during pregnancy may damage DNA methylation and histone modifications of pre-implantation embryo. We provide prevent the harm of alcohol to the fetus.

在父性、母性孕期酒精暴露研究中，怀孕期间酒精摄入对植入前胚胎DNA甲基化及组蛋白修饰可能造成损害的差异，也为我们预防酒精对胎儿的伤害提供借鉴的作用。

It is generally believed that the low efficiency of cloning is due to the incorrect or incomplete nuclear reprogramming of the differentiated somatic cells after nuclear transfer. One of which is the abnormal DNA methylation and histone modifications.

一般认为克隆效率低下与重构胚不正确或者不完全的重组而导致的错误表观修饰相关，其中最主要的就是DNA甲基化异常和组蛋白修饰错误。

Chromatin immunoprecipitation assay ( ChIP) provides a powerful tool to analyze the interaction of trans-acting factors with specific chromatin regions in vivo, as well as the role of histone modifications in gene regulation.

染色质免疫沉淀法是研究染色质结构的首选方法，它不仅可用来研究体内反式因子与DNA的相互作用，也可以用来研究组蛋白修饰与基因表达的关系。

DNA Methylation, Histone Modifications and Genes Silencing

DNA甲基化、组蛋白修饰与基因沉默

Based on those disadvantages of traditional methods, the study for DNA demethylation and the relationship between DNA methylation and histone modification are difficult.

因此，也就为研究DNA去甲基化以及DNA甲基化与组蛋白修饰之间的关系造成了麻烦。

Recently studies suggested that, such as DNA methylation and histone acetylation, could affect directly the cloning efficiency and transgene expression during reprogramming process of somatic cells.

已有的研究表明，体细胞重编程过程中，DNA甲基化、组蛋白乙酰化对克隆效率和转基因表达都有直接的影响。

Histone posttranslational modifications and sequence variants jointly participate in modification of chromatin and regulation of gene expression.

组蛋白的变体和翻译后修饰共同参与染色质修饰和基因的表观遗传调控。

Histone methylation is an important component of epigenetic regulation, which can regulate gene expression and participate in a variety of biological processes.

组蛋白甲基化是表观遗传调控的一种重要方式，与基因的转录调控密切相关，参与多种生物进程。