overexpression的例句大全

Overexpression of bcl-2 gene was found in all cases; 1 of 11 cases had t ( 14,18) ( q32, q21) translations.

我们应用免疫组化染色和聚合酶链反应检测了11例慢性淋巴细胞白血病bcl-2基因表达和重排，结果发现所有病例均高度表达Bcl-2蛋白，1例有t（14,18）（q32，q21）染色体易位。

Construction and appreciation of p50 gene cells stable overexpression

稳定过表达p50基因细胞株的构建及鉴定

Also, overexpression of p18~ ( INK4C) in K562 cells resulted in G0/ G1 arrest and partial erythroid differentiation.

在K562细胞中过表达p18~（INK4C）基因可诱导细胞G0/G1期阻滞和部分红系分化。

Cell cycles were blocked in G1 stage. Conclusion Overexpression of PTEN will induce G1 arrest in rar renal fibroblast cells, which associated with the nuclear location of PTEN.

结论PTEN过度表达将引起肾脏成纤维细胞周期G1期阻滞，这一过程与PTEN在细胞核定位有关。

Cloning and overexpression of rat ovary LH/ hcg receptor cDNA in insect cells

大鼠卵巢促黄体激素/人绒毛膜促性腺激素受体cDNA的克隆和在昆虫细胞中的高效表达

Treatment with F_2 before hypoxia and reoxygenation significantly attenuated the cardiomyocytes injury and inhibited the overexpression of Egr-1 after H/ R.

缺氧及复氧前给予F2则能改善H/R所致心肌细胞病理损害，抑制心肌细胞Egr-1的过量表达。

Objective Construction of transgenic mice with selective brain overexpression of Kynureninase ( Kynu) to investigate the effect of increased KYNU activity on blood pressure ( BP).

目的本研究旨在构建脑组织选择性过表达犬尿氨酸酶（Kynu）的转基因小鼠，在整体水平研究KYNU活性增强对血压的影响。

Conclusion: There is a COX-2 overexpression in ovarian carcinoma. Inactivation of antioncogene p53 and overexpression of COX-2 may play an interaction in the development of ovarian carcinoma.

结论：卵巢癌组织中存在COX-2的过表达，COX-2过表达及抑癌基因P53的失活在卵巢癌的形成过程中可能具有相互促进的作用。

Conclusion There is mutant-type p53 and MDM2 protein overexpression in NHL. The p53 gene inactivation resulting from MDM2 protein over expression and/ or p53 gene mutation may play all important role in NHL.

结论p53和MDM2蛋白在NHL病理组织中均呈高表达，MDM2蛋白和/或p53基因突变使p53基因功能失活在NHL发生中可能有重要作用。

Conclusions The overexpression of MMP 2 and MMP 9 may be correlated with the remodelling of blood tumor barrier in human brain glioma.

结论MMP-2、MMP-9与人脑胶质瘤侵袭微生态系统中血瘤屏障的改造重建有关。

It has been proved that the main but not the only causes for the drug resistance of RCC are the overexpression of P-glycoprotein ( P-gp) and the activity increase of Glutathione ( GSH)-dependent detoxication enzyme system.

目前研究证实P-糖蛋白（P-gp）过度表达以及谷胱甘肽依赖性解毒酶系统活性增高在介导肾癌对化疗药物的耐受过程中发挥了重要作用，但上述因素并非是化疗药物耐药的唯一途径。

Moreover, the overexpression of TALL 1 in transgenic mice can result in severe B cell hyperplasia and autoimmune lupus like disease.

另外，TALL1在转基因鼠中的过量表达可引起严重的B细胞增生以及与狼疮有关的自身免疫性疾病。

These results demonstrate that overexpression of COX-2 can lead to phenotypic changes that alter the metastatic and angiogenic potential of TCC cancer cells.

结论：COX-2的过表达能促进EJ肿瘤细胞侵袭转移和血管生成能力表型方面的改变，即COX-2能促进肿瘤细胞体外侵袭能力的增强和促血管生成能力的增强。

Overexpression of Egr-1 promotes epithelial-to-mesenchymal transition on renal tubular epithelial cells

早期生长反应因子1过表达促进肾小管上皮细胞转分化

[ Conclusions] The A549/ TXL20 cell line shows drug resistant phenotype and may be related to overexpression of DNA pol β.

结论A549/TXL20具有多药耐药表型，耐药性产生可能与细胞内DNA polβ表达增高有关。

effect of overexpression of maize ppc gene on photosynthesis in transgenic rice plants

玉米ppc基因过表达对转基因水稻光合速率的影响

background and purpose: drug-resistance is the main obstacle in terms of efficacy of chemotherapy for leukemia, rna interference ( rnai) strategy possesses the characteristics of specilization, high-efficiency and low-toxicity, and can effectively and specifically inhibit the overexpression of given gene.

背景与目的白血病耐药性是白血病治疗中的难点，RNAi技术具有特异、高效、毒性小的特点，可高效、特异地抑制特定基因的过度表达。

However, in HCC with Fas expression, the ratio of apoptosis increased significantly and PCNA-LI remained, it means that the apoptosis could be promoted by the overexpression of Fas.

FaS阳性HCC细胞凋亡指数显著增高，而PCNA一LI改变不显著，提示Fas蛋白过度表达可促进HCC的细胞凋亡，而对其细胞增殖可能影响不大。

mutation, overexpression, or amplification of oncogenes in somatic cells may lead to neoplastic transformation.

体细胞癌基因的活化方式为突变、过表达和扩增。

biological characters of a multidrug resistance-related protein overexpression subline of the bladder carcinoma

膀胱癌稳定表达多药耐受相关蛋白亚克隆的生物学特征